Breast cancer treatment has seen remarkable progress, with a notable shift towards balancing improved survival with better aesthetic results. The rise in early detection through mammography and the identification of high-risk individuals through genetic testing, has led to an increase in preventive surgeries. Within this evolved landscape, nipple-sparing mastectomy (NSM) and skin-sparing mastectomy (SSM) with immediate reconstruction have gained prominence, offering improved quality of life and aesthetic benefits. However, there is a gap in research regarding the oncologic safety of NSM, especially within the Danish population.
Our project is designed to fill this gap by evaluating the oncologic outcomes of NSM and SSM in patients with invasive breast cancer, DCIS, and those at high risk opting for preventive mastectomies. We aim to analyze recurrence rates and survival outcomes, alongside the role of mammographic measurements in surgical planning, through four interconnected studies. The ultimate goal is to refine patient counseling and enhance the decision-making process for women considering mastectomy with reconstruction.
The significance of this research lies in its potential to inform clinical practice, ensuring the availability of safe reconstructive options. We place a strong emphasis on patient-centered care, recognizing the profound impact of mastectomy on a woman’s body image and psychological well-being. Our approach is to empower patients with data-driven choices, advocating for their active role in treatment decisions.
Moreover, this project is a step towards innovation in breast cancer management, advancing surgical oncology and reinforcing patient confidence in nipple-preserving procedures. By setting a benchmark for evidence-based practices, we aim not only to advance patient care but also to inspire future breakthroughs in treatment options, enhancing both survival and quality of life for women facing breast cancer.
Resident, Alexandra Golembiovska Frydkjær, Gentofte Hospital